Greetings Dvc3,
Welcome to the forum.
I am not a HP employee.
You could have a hardware problem (storage device, RAM, or disk controller/SATA port). Any flaky hardware drivers or hardware including dirty power can cause weird stuff.
Run HP Diagnostics.
Tap "ESC".
Select "F2".
Run system and components tests.
Run a check disk to check (Link)system files.
You said you tried typical Window's recovery procedures: resets, system restores, and startup repair.
A Windows corruption problem should have been resolved by doing a reset.
Back up data (if possible), try a clean W10 install on one of the SSDs to see how it goes.
Regards