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Where to install 2nd graphics card on 3 slot dual zeon z840

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Microsoft Windows 10 (64-bit)

I have a dual xeon z-840 with 3 PCIe-x16 slots

The first 2 PCIe-x16 slots got to the 1st CPU

The 3rd PCIe-x16 slot goes to the 2nd CPU


Where is the best place to put the 2nd Graphics Card?


I was thinking slot 3 so the 2nd CPU can handle it but does that CPU still have to get instructions from the 1st anyway?


Thanks for any help.


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