The Quadro M5000 should work in a z800 and there are users running Maxwell GTX GPUs. Still checking the 666 Passmark Performance Test Results for the z800, it's odd that there is no listing for the M5000, M4000, nor M2000. However there are results for Kepler series cards (K4000, K5000, and K6000). It may be that the Quadro M5000 was released years after the z800 and was quite expensive - US $1,900 and z800's when depreciated three years would not have been subjects for that level of investment.
I should contact HP support or perhaps someone from HP will please comment here.
[Passmark Rating = 6166 / CPU rating = 16934 / 2D = 820 / 3D= 8849 / Mem = 2991 / Disk = 13794] 4.24.17 Single Thread Mark = 2252
On Passmark results, the average 3D Mark for the Quadro M5000 is 8506. The average for the P2000 is 8652, making the P2000 as fast as a GTX 1060, faster than GTX Titan Black, Quadro M5000, and Quadro K6000. In HP systems (10 tested) the range of 3D marks for the Quadro M5000 is 7241 (z600 / 2X X5670) to 10797 (z240/ i7-6700K). The z240 results is the second highest of any result for the Quadro M5000.
The very good news concerning the P2000 is that my cost in the U.S. was $412 which = less than 1/4th the cost of a new M5000. Also, the P2000 only uses 75W, and therefore does not need an auxiliiary power connection. a Quadro P4000 (US $ 850) is close (10591) to being as fast as a GTX Titan X (10657) and is faster than a Quadro M6000- $5,000 (9421). Of course, those cards will have a benefit from having considerably more memory if the use is video processing / animation.
Be sure that the BIOS and chipset driver is the latest version to use any Maxwell, Kepler, and especially Pascal GPU.
Again, I hope someone from HP will copmment on Maxwell and Pascal GPU's in a z800.
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