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roglin Student
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Unable to initiate HotSync operation because the port is in use by another application.

When I try to HotSync my Palm Centro I get the following error Message:

 

Unable to initiate HotSync operation because the port is in use by another application.

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Teacher Teacher
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Unable to initiate HotSync operation because the port is in use by another application.

The steps resolve this issue is provided in the following document in detail:

 

http://kb.hpwebos.com/wps/portal/kb/common/article/31375_en.html

 

Hope this helps!

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........................just trying to help where I can, but not speaking on behalf of HP.

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Ed75 Honor Student
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Unable to initiate HotSync operation because the port is in use by another application.

On PC  Sync settings set connection to cable then set to bluetooth.  Problem fixed.

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CaliforniaBrit Honor Student
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Unable to initiate HotSync operation because the port is in use by another application.

This site was shut down by HP in May 2015.

I also tried another contributor's solution "On PC  Sync settings set connection to cable then set to bluetooth.  Problem fixed." I have no "cable" opyion, but unchecking cradle, IR, etc then checking "Bluetooth", in any combination, including closing Desktop and reopening, failed to work. 

This and other similar problems have all arisen since upgrading to Win 10.

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