If the defrag utility you mention is the one included in HP Support Assistant, try the following.
First of all, uninstall your current version of HP Support Assistant by opening windows Control Panel, open Programs and Features, right click the entry for HP Support Assistant and select Uninstall. When this process has completed, restart the PC.
Next download and install the latest version of HP Support Assistant from the page on the link below - the download links are towards the bottom of the page.
I uninstalled and then reinstalled HP Support Assistant following your instructions. Everything went smoothly. I ran a Tune Up on the newly installed version and tha was fine. What I noticed is that the Tune Up does no include disk defrag. It set a restore point, cleared IE Temp files and Temp folders, analyzed the computer for hardware and software issues and prepared the action list.
So my assumption is to run the disk defrag via Windows?