I installed Palm Desktop 6.2.2 on my Windows 10 system, sync'd and all was working fine for about 30 days or so. The other day I started my computer, went to the Palm Desktop and found all of the folders (in the left panel) are gone EXCEPT Media and Install. I have Uninstalled and reinstalled many times (from stored and newly downloaded sources) and still have the same problem.
Since installing Windows 10 I have found Microsoft trying to establish it's applications as the default with quite a few applications (a real fight with MS / Chrome and MS / Adobe PDF).
At this time, the only folder I can sync is Photo's. All other folders appear to sync but do not show up in the left verticle nav bar.