Hi,
Are you trying to install Windows 10?
You need to enter BIOS at startup. Leave the drive in USB port. To enter Bios at startup press esc after starting the computer and go to boot order. You should see the pendrive in the list. Move it up to the top of the list , save and reboot the computer. Now you will need to press a key when prompted to boot from pendrive and windows 10 installation will start.
Let me know ìf you need further help,
David