Resolve Windows 10 related issues for your HP computers or printers by HP Windows 10 Support Center
There are a couple of possibilities.
1. You have usb in first place in boot order and have pen drives attached to your PC. The computer is trying to boot from these drives.
Change boot order in Bios.
2. Your hard drive has become corrupted and the PC is trying to boot from pendrive.
3. Your hard drive has failed and needs to be replaced.
Try performing a HP diagnostics of the system at boot by pressing F2.
Let me know,
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